SAM e S Adenosylmethionine is a chiral molecule and therefore consists of two forms S,S SAM e and R,S SAM e. The biologically active form is the S,S structure, while the R,S structure is biologically inactive. Jarrow Formulas' SAM e is made naturally by microbiological fermentation and then specially processed to preserve 68 80% S,S SAM e, the highest active level available. SAM e is an amino acid derivative that has been clinically proven to benefit brain, joint and liver function. Found in all living cells, SAM e is also called activated methionine an essential amino acid since it is formed by the combining of ATP with methionine. SAM e has undergone dozens of trials involving thousands of patients. Researchers studying the beneficial effects of SAM e have identified the following benefits of SAM e Joint Strength Brain Metabolism Longevity Liver The Inside Scoop SAM e 400 is foil blister packed to maximize stability and safety. Do not use if seal of blister p