Jarrow Formulas' SAMe 200 contains pharmaceutical grade stabilized S Adenosyl Methionine SAMe, a naturally occurring compound produced by the body. SAMe is formed when the body combines the amino acid L methionine with ATP adenosine triphosphate, the primary energy molecule found in physiologic processes. SAMe may be the most active and efficient of the various methyl donors currently known. SAMe is considered The Active Methionine. It is utilized for transmethylation, transulfuration and amino propylation. The amount of SAMe available to the body typically declines with age. Suggested Use Take 1 to 3 tablets per day before meal, or as directed by your qualified health consultant.